Brain-Gut Interactions in IBS
نویسندگان
چکیده
منابع مشابه
Brain-Gut Interactions in IBS
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder with an estimated prevalence of 10-20%. Current understanding of the pathophysiology of IBS is incomplete due to the lack of a clearly identified pathological abnormality and due to the lack of reliable biomarkers. Possible mechanisms believed to contribute to IBS development and IBS like symptoms include physical stressors, s...
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Psycho-neuro-endocrine-immune modulation through the brain-gut axis likely has a key role in the pathogenesis of inflammatory bowel diseases (IBD). The brain-gut axis involves interactions between the neural components including; a) the autonomic nervous system, b) the central nervous system c) the stress system (hypothalamic-pituitary adrenal axis, HPA) and d) the (i.e. gastro-intestinal) cort...
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Psycho-neuro-endocrine-immune modulation through the brain-gut axis likely has a key role in the pathogenesis of inflammatory bowel disease (IBD). The brain-gut axis involves interactions among the neural components, including (1) the autonomic nervous system, (2) the central nervous system, (3) the stress system (hypothalamic-pituitary-adrenal axis), (4) the (gastrointestinal) corticotropin-re...
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Although IBS is the most common functional disorder of alimentary tract in western countries, its pathogenesis is still not fully understood. It seems that multiple precipitating factors alter gut motility and visceral perception, resulting in specific motor function disorders. These disorders seem to differ between patients presenting with constipation and those presenting with diarrhea. The m...
متن کاملDo gut microbial communities differ in pediatric IBS and health?
Human gastrointestinal microbial communities are recognized as important determinants of the host health and disease status. We have recently examined the distal gut microbiota of two groups of children: healthy adolescents and those diagnosed with diarrhea-predominant irritable bowel syndrome (IBS). We have revealed the common core of phylotypes shared among all children, identified genera dif...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2012
ISSN: 1663-9812
DOI: 10.3389/fphar.2012.00127